Coordinating the morphogenesis-differentiation balance by tweaking the cytokinin-gibberellin equilibrium
Autoři:
Alon Israeli aff001; Yogev Burko aff001; Sharona Shleizer-Burko aff001; Iris Daphne Zelnik aff001; Noa Sela aff002; Mohammad R. Hajirezaei aff003; Alisdair R. Fernie aff004; Takayuki Tohge aff004; Naomi Ori aff001; Maya Bar aff001
Působiště autorů:
The Robert H. Smith Institute of Plant Sciences and Genetics in Agriculture, Hebrew University, Rehovot, Israel
aff001; Department of Plant Pathology and Weed Research, Plant Protection Institute, Agricultural Research Organization, Volcani Institute, Rishon LeZion, Israel
aff002; Molecular Plant Nutrition, Department of Physiology and Cell Biology, Leibniz Institute of Plant Genetics and Crop Plant Research, Seeland, Germany
aff003; Max-Planck-Institute of Molecular Plant Physiology, Potsdam-Golm, Germany
aff004
Vyšlo v časopise:
Coordinating the morphogenesis-differentiation balance by tweaking the cytokinin-gibberellin equilibrium. PLoS Genet 17(4): e1009537. doi:10.1371/journal.pgen.1009537
Kategorie:
Research Article
doi:
https://doi.org/10.1371/journal.pgen.1009537
Souhrn
Morphogenesis and differentiation are important stages in organ development and shape determination. However, how they are balanced and tuned during development is not fully understood. In the compound leaved tomato, an extended morphogenesis phase allows for the initiation of leaflets, resulting in the compound form. Maintaining a prolonged morphogenetic phase in early stages of compound-leaf development in tomato is dependent on delayed activity of several factors that promote differentiation, including the CIN-TCP transcription factor (TF) LA, the MYB TF CLAU and the plant hormone Gibberellin (GA), as well as on the morphogenesis-promoting activity of the plant hormone cytokinin (CK). Here, we investigated the genetic regulation of the morphogenesis-differentiation balance by studying the relationship between LA, CLAU, TKN2, CK and GA. Our genetic and molecular examination suggest that LA is expressed earlier and more broadly than CLAU and determines the developmental context of CLAU activity. Genetic interaction analysis indicates that LA and CLAU likely promote differentiation in parallel genetic pathways. These pathways converge downstream on tuning the balance between CK and GA. Comprehensive transcriptomic analyses support the genetic data and provide insights into the broader molecular basis of differentiation and morphogenesis processes in plants.
Klíčová slova:
Graphs – Hyperexpression techniques – Leaf development – Leaves – Morphogenesis – Phenotypes – Tomatoes – Transcription factors
Zdroje
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