The importance of adherence in tuberculosis treatment clinical trials and its relevance in explanatory and pragmatic trials
Autoři:
Andrew Vernon aff001; Katherine Fielding aff002; Rada Savic aff004; Lori Dodd aff005; Payam Nahid aff006
Působiště autorů:
Clinical Research Branch, Division of TB Elimination, NCHHSTP, US Centers for Disease Control & Prevention, Atlanta, Georgia, United States of America
aff001; TB Centre, London School of Hygiene & Tropical Medicine, London, United Kingdom
aff002; Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa
aff003; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, California, United States of America
aff004; National Institute for Allergy and Infectious Disease, National Institutes of Health, Washington DC, United States of America
aff005; Division of Pulmonary and Critical Care Medicine, University of California, San Francisco at San Francisco General Hospital, San Francisco, California, United States of America
aff006
Vyšlo v časopise:
The importance of adherence in tuberculosis treatment clinical trials and its relevance in explanatory and pragmatic trials. PLoS Med 16(12): e32767. doi:10.1371/journal.pmed.1002884
Kategorie:
Collection Review
doi:
https://doi.org/10.1371/journal.pmed.1002884
Souhrn
Andrew Vernon and co-authors discuss adherence to therapy and its measurement in tuberculosis treatment trials.
Klíčová slova:
Clinical trials – Drug adherence – Drug metabolism – Drug screening – Ingestion – Pharmacokinetics – Tuberculosis – Urine
Zdroje
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