Herbs for increasing breast-milk production

Česká verze

Authors: Zuzana Vargová; Jana Rudá-Kučerová
Published in the journal: Čes. slov. Farm., 2017; 66, 208-219
Category: Přehledy a odborná sdělení

Summary

Subjective perception of insufficient milk supply is one of the most common problems of nursing mothers. For centuries, herbs have been used to increase lactation and remain popular even today. There is only a limited number of studies proving their safety and effectivity, so their use is based primarily on previous experience. The use of certain herbs has shown that they could be effective and safe, but further research is needed to define terms of use. This paper describes preliminary findings on the mechanism of action, adverse effects and possible interactions observed in some herbs frequently used to promote lactation.

Key words:
phytotherapy • lactation • herbal galactagogue

Zdroje

1. WHO | Breastfeeding. WHO. http://www.who.int/topics/breastfeeding/en/

2. Zwinger A. Porodnictví. 1. vydání. Praha: Galén 2004; 158–163.

3. Blackburn S. T. Maternal, fetal, & neonatal physiology: a clinical perspective. 4th ed. Amsterdam: Elsevier Saunders 2013; 719.

4. Ben-Jonathan N., Hnasko R. Dopamine as a prolactin (PRL) inhibitor. Endocr Rev. 2001; 22(6), 724–763.

5. Penagos Tabares F., Bedoya Jaramillo J. V., Ruiz-Cortés Z. T. Pharmacological overview of galactogogues. Vet. Med. Int. 2014; 2014, 602894.

6. Státní ústav pro kontrolu léčiv. Upozornění SÚKL – použití domperidonu off-label ke zvýšení laktace. Dostupné z: http://www.sukl.cz/upozorneni-sukl-pouziti-domperidonu-off-label-ke-zvyseni

7. Litavec M. Užívanie liekov s obsahom Domperidónu off-label na zvýšenie tvorby materského mlieka. Dostupné z: http://institutdojcenia.sk/wp-content/uploads/2015/04/Uzivanie-liekov-s-obsahom-Domperidonu-na-zvysenie-tvorby-materskeho-mlieka.pdf

8. Státní ústav pro kontrolu léčiv. MOTILIUM, 10MG TBL FLM 30. Dostupné z: http://www.sukl.cz/modules/medication/detail.php?code=0047271&tab=texts

9. Bazzano A. N., Hofer R., Thibeau S., Gillispie V., Jacobs M., Theall K. P. A Review of Herbal and Pharmaceutical Galactagogues for Breast-Feeding. Ochsner J. 2016; 16(4), 511–524.

10. Sim T. F., Hattingh H. L., Sherriff J., Tee L. B. G. Perspectives and attitudes of breastfeeding women using herbal galactagogues during breastfeeding: a qualitative study. BMC Complement Altern. Med. 2014; 14, 216.

11. Gori L., Gallo E., Mascherini V., Mugelli A., Vannacci A., Firenzuoli F. Can Estragole in Fennel Seed Decoctions Really Be Considered a Danger for Human Health? A Fennel Safety Update. Evid Based Complement Alternat. Med. 2012; e860542.

12. Badgujar S. B., Patel V. V., Bandivdekar A. H. Foeniculum vulgare Mill: A Review of Its Botany, Phytochemistry, Pharmacology, Contemporary Application, and Toxicology. BioMed Res. Int. 2014; 1–32.

13. Assesment report on Foeniculum vulgare Miller, fructus, Comittee on Herbal Medicinal Products (HMPC), European Medicines Agency 2008. Dostupné z: http://www.ema.europa.eu/docs/en_GB/document_library/Herbal_-_HMPC_assessment_report/2009/12/WC500018463.pdf

14. Bone K., Mills S. Principles and practice of phytotherapy: modern herbal medicine. 2nd ed. Edinburgh: Churchill Livingstone, Elsevier 2013.

15. Foong S. C., Tan M. L., Marasco L. A., Ho J. J., Foong W. C. Oral galactagogues for increasing breast-milk production in mothers of non-hospitalised term infants. In: The Cochrane Collaboration, editor. Cochrane Database of Systematic Reviews. Chichester, UK: John Wiley & Sons, Ltd; 2015. . Dostupné z: http://doi.wiley.com/10.1002/14651858.CD011505

16. Nahid S., Afshin K. A., Alireza N., Homayun D., Azadeh M. Study of Foeniculum vulgare (Fennel) Seed Extract Effects on Serum Level of Estrogen, Progesterone and Prolactin in Mouse. Crescent J. Med. Biol. Sci. 2015; 2(1), 23–27.

17. Honarvar F., Tadayon M., Afshari P. The effect of foeniculum vulgare on serum prolactin level in lactating women. Iran J. Obstet. Gynecol. Infertil. 2013; (16), 18–24.

18. Abascal K., Yarnell E. Botanical Galactagogues. Altern. Complement Ther. 2008; 14(6), 288–294.

19. Langhammer A. J., Nilsen O. G. In vitro inhibition of human CYP1A2, CYP2D6, and CYP3A4 by six herbs commonly used in pregnancy. Phytother. Res. 2014; 28(4), 603–610.

20. Sadati S. N., Ardekani M. R. S., Ebadi N., Yakhchali M., Dana A. R., Masoomi F., et al. Review of scientific evidence of medicinal convoy plants in traditional Persian Medicine. Pharmacogn. Rev. 2016; 10(19), 33–38.

21. El-Soud N., El-Laithy N., El-Saeed G., Wahby M., Khalil M., Morsy F., et al. Antidiabetic activities of Foeniculum vulgare Mill. Essential oil in streptozotocin-induced diabetic rats. Maced. J. Med. Sci. 2011; 4(2), 139–146.

22. Mostafa D. M., Abd El-Alim S. H., Asfour M. H., Al-Okbi S. Y., Mohamed D. A., Awad G. Transdermal nanoemulsions of Foeniculum vulgare Mill. Essential oil: Preparation, characterization and evaluation of antidiabetic potential. J. Drug. Deliv. Sci. Technol. 2015; 29, 99–106.

23. Assessment report on Carum carvi L., fructus and Carum carvi L., Aetheroleum, Comittee on Herbal Medicinal Products (HMPC), European Medicines Agency 2015. Dostupné z: http://www.ema.europa.eu/docs/en_GB/document_library/Herbal_-_HMPC_assessment_report/2015/09/WC500193273.pdf

24. Dadkhah M. A., Yeganehzad M. The effects of extracts of plants (Medicago Sativa, Trigonella Foenum and Carum Carvi) on milk production in dairy cow. Adv. Environ. Biol. 2011; 3129–3135.

25. Stapleton H. The use of herbal medicine in pregnancy and labour. Part II: Events after birth, including those affecting the health of babies. Complement Ther Nurs. Midwifery 1995; 1, 165–167.

26. Kazemipoor M., Radzi C., Hajifaraji M., Cordell G. A. Preliminary safety evaluation and biochemical efficacy of a Carum carvi extract: results from a randomized, triple-blind, and placebo-controlled clinical trial. Phytother. Res. 2014; 28(10), 1456–1460.

27. el-Shobaki F. A., Saleh Z. A., Saleh N. The effect of some beverage extracts on intestinal iron absorption. Z Ernahrungswiss 1990; 29(4), 264–269.

28. Choudhary N., Khajuria V., Gillani Z. H., Tandon V. R., Arora E. Effect of Carum carvi, a herbal bioenhancer on pharmacokinetics of antitubercular drugs: A study in healthy human volunteers. Perspect. Clin. Res. 2014; 5(2), 80–84.

29. Sachin B. S., Monica P., Sharma S. C., Satti N. K., Tikoo M. K., Tikoo A. K. Pharmacokinetic interaction of some antitubercular drugs with caraway: implications in the enhancement of drug bioavailability. Hum. Exp. Toxicol. 2009; 28(4), 175–184.

30. Naghibi S., Ramezani M., Ayati N., Zakavi S. Carum induced hypothyroidism: an interesting observation and an experiment. DARU J. Pharm. Sci. 2015; 23(1), 5.

31. Lahlou S., Tahraoui A., Israili Z., Lyoussi B. Diuretic activity of the aqueous extracts of Carum carvi and Tanacetum vulgare in normal rats. J. Ethnopharmacol. 2007; 110(3), 458–463.

32. Johri R. K. Cuminum cyminum and Carum carvi: An update. Pharmacogn. Rev. 2011; 5(9), 63–72.

33. Agrahari P., Singh D. K. A review on the pharmacological aspects of Carum carvi. J. Biol. Earth Sci. 2014; 4(1), 1–13.

34. González‐Andrés F., Redondo P. A., Pescador R., Urbano B. Management of Galega officinalis L. and preliminary results on its potential for milk production improvement in sheep. N Z J Agric. Res. 2004; 47(2), 233–245.

35. Bajaj Y. P. S. Legumes and Oilseed Crops I. Springer Science & Business Media 2012.

36. Zecca E., Zuppa A. A., D’Antuono A., Tiberi E., Giordano L., Pianini T. Efficacy of a galactogogue containing silymarin-phosphatidylserine and galega in mothers of preterm infants: a randomized controlled trial. Eur. J. Clin. Nutr. 2016; 70(10), 1151–1154.

37. Rasekh H. R., Nazari P., Kamli-Nejad M., Hosseinzadeh L. Acute and subchronic oral toxicity of Galega officinalis in rats. J. Ethnopharmacol. 2008; 116(1), 21–26.

38. Koupý D., Kotolová H., Kučerová J. Současné fytoterapeutické možnosti v léčbě diabetes mellitus. Prakt. Lékárenství 2014; 10(6), 229–232.

39. Atanasov A. T., Tchorbanov B. Anti-Platelet Fraction from Galega officinalis L. Inhibits Platelet Aggregation. J. Med. Food 2002; 5(4), 229–234.

40. Assessment report on Pimpinella anisum L., fructus and Pimpinella anisum L., aetheroleum, Comittee on Herbal Medicinal Products (HMPC), European Medicines Agency 2014. Dostupné z: http://www.ema.europa.eu/docs/en_GB/document_library/Herbal_-_HMPC_assessment_report/2014/06/WC500168971.pdf

41. Hosseinzadeh H., Tafaghodi M., Abedzadeh S., Taghiabadi E. Effect of aqueous and ethanolic extracts of Pimpinella anisum L. seeds on milk production in rats. J. Acupunct. Meridian Stud. 2014; 7(4), 211–216.

42. Tisserand R., Young R. Essential Oil Safety. 2nd ed. Elsevier 2014; 187–482.

43. Gori L., Gallo E., Mascherini V., Mugelli A., Vannacci A., Firenzuoli F. Can estragole in fennel seed decoctions really be considered a danger for human health? A fennel safety update. Evid-Based Complement Altern. Med. 2012; 2012, 860542.

44. Shojaii A., Abdollahi Fard M. Review of Pharmacological Properties and Chemical Constituents of Pimpinella anisum. ISRN Pharm. 2012; 2012, 1–8.

45. Samojlik I., Mijatović V., Petković S., Skrbić B., Božin B. The influence of essential oil of aniseed (Pimpinella anisum, L.) on drug effects on the central nervous system. Fitoterapia 2012; 83(8), 1466–1473.

46. Rajeshwari U., Shobha I., Andallu B. Comparison of aniseeds and coriander seeds for antidiabetic, hypolipidemic and antioxidant activities. Spatula DD – Peer Rev. J. Complement Med. Drug. Discov. 2011; 1(1), 9.

47. Baumgardner D. Stinging nettle: the bad, the good, the unknown. J. Patient-Centered Res. Rev. 2016; 3(1), 48–53.

48. Upton R. Stinging nettles leaf (Urtica dioica L.): Extraordinary vegetable medicine. J. Herb. Med. 2013; 3(1), 9–38.

49. Assessment report on Urtica dioica L., Urtica urens L., folium, Comittee on Herbal Medicinal Products (HMPC), European Medicines Agency 2011. Dostupné z: http://www.ema.europa.eu/docs/en_GB/document_library/Herbal_-_HMPC_assessment_report/2011/01/WC500100760.pdf

50. Westfall R. E. Herbal medicine in pregnancy and childbirth. Adv. Ther. 2001; 18(1), 47–55.

51. Ishikawa T., Kudo M., Kitajima J. Water-soluble constituents of dill. Chem. Pharm. Bull. (Tokyo) 2002; 50(4), 501–507.

52. Chahal K. K., Kumar M. A., Bhardwaj U., Kaur R. Chemistry and biological activities of Anethum graveolens L. (dill) essential oil: A review. J. Pharmacogn. Phytochem. 2017; 6(2), 295–306.

53. Jana S., Shekhawat G. S. Anethum graveolens: An Indian traditional medicinal herb and spice. Pharmacogn. Rev. 2010; 4(8), 179–184.

54. Snafi A. A. The pharmacological importance of Anethum graveolens. A review. Int. J. . Pharm. Sci. 2014; 6(4).

55. Zeng H., Tian J., Zheng Y., Ban X., Zeng J., Mao Y. In Vitro and In Vivo Activities of Essential Oil from the Seed of Anethum graveolens L. against Candida spp. Evid. Based Complement Alternat. Med. 2011; 2011, 1–8.

56. Saini N., Singh G. K., Nagori B. P. Spasmolytic potential of some medicinal plants belonging to family umbelliferae: A review. Int. J. Res. AYURVEDA Pharm. 2014; 5(1), 74–83.

57. Goodarzi M. T., Khodadadi I., Tavilani H., Abbasi Oshaghi E. The role of Anethum graveolens L. (Dill) in the management of diabetes. J. Trop. Med. 2016; 2016, 1–11.

58. Lazutka J. R., Mierauskiene J., Slapsyte G., Dedonyte V. Genotoxicity of dill (Anethum graveolens L.), peppermint (Menthaxpiperita L.) and pine (Pinus sylvestris L.) essential oils in human lymphocytes and Drosophila melanogaster. Food Chem. Toxicol. Int. J. Publ. Br. Ind. Biol. Res. Assoc. 2001; 39(5), 485–492.

59. Malihezaman M., Mojaba M., Elham H., Farnaz G., Ramin M. Anti-Fertility Effects of Different Fractions of Anethum Graveolens L. Extracts on Female Rats. Afr. J. Tradit. Complement Altern. Med. 2012; 9(3), 336–341.

60. Monsefi M., Ghasemi A., Alaee S., Aliabadi E. Effects of Anethum graveolens L. (dill) on Oocyte and Fertility of Adult Female Rats. J. Reprod. Infertil. 2015; 16(1), 10–17.

61. Bazzano A. N., Cenac L., Brandt A. J., Barnett J., Thibeau S., Theall K. P. Maternal experiences with and sources of information on galactagogues to support lactation: a cross-sectional study. Int. J. Womens Health 2017; 9, 105–113.

62. Assessment report on Trigonella foenum-graecum L., semen, Comittee on Herbal Medicinal Products (HMPC), European Medicines Agency 2010.

63. Snehlata H. S., Payal D. R. Fenugreek (Trigonella foenum-graecum L.): An overview. J. Curr. Pharm. Rev. Res. 2012; 2(4), 169–187.

64. Alamer M. A., Basiouni G. F. Feeding Effects of Fenugreek Seeds (Trigonella foenum-graecum L.) on Lactation Performance, Some Plasma Constituents and Growth Hormone Level in Goats. Pak. J. Biol. Sci. 2005; 8(11), 1553–1556.

65. Yadav U. C. S., Baquer N. Z. Pharmacological effects of Trigonella foenum-graecum L. in health and disease. Pharm. Biol. 2014; 52(2), 243–254.

66. Basch E., Ulbricht C., Kuo G., Szapary P., Smith M. Therapeutic applications of fenugreek. Altern. Med. Rev. J. Clin. Ther. 2003; 8(1), 20–27.

67. Budzynska K., Gardner Z. E., Dog T. L., Gardiner P. Complementary, Holistic, and Integrative Medicine: Advice for Clinicians on Herbs and Breastfeeding. Pediatr. Rev. 2013; 34(8), 343–353.

68. Ouzir M., El Bairi K., Amzazi S. Toxicological properties of fenugreek (Trigonella foenum graecum). Food Chem. Toxicol. 2016; 96, 145–154.

69. Khalki L., M’hamed S. B., Bennis M., Chait A., Sokar Z. Evaluation of the developmental toxicity of the aqueous extract from Trigonella foenum-graecum (L.) in mice. J. Ethnopharmacol. 2010; 131(2), 321–325.

70. Koupý D., Kotolová H., Rudá Kučerová J. Effectiveness of phytotherapy in supportive treatment of type 2 diabetes mellitus II. Fenugreek (Trigonella foenum-graecum). Ces. slov. Farm. 2015; 64(3), 67–71.

71. Ulbricht C., Basch E., Dacey C., Dith S., Hammerness P., Hashmi S. An evidence-based systematic review of blessed thistle (Cnicus benedictus) by the natural standard research collaboration. J. Diet. Suppl. 2008; 5(4), 422–437.

72. Sim T. F., Hattingh H. L., Sherriff J., Tee L. B. G. The Use, Perceived Effectiveness and Safety of Herbal Galactagogues During Breastfeeding: A Qualitative Study. Int. J. Environ Res. Public. Health 2015; 12(9), 11050–11071.

73. Alok S., Jain S. K., Verma A., Kumar M., Mahor A., Sabharwal M. Plant profile, phytochemistry and pharmacology of Asparagus racemosus (Shatavari): A review. Asian Pac. J. Trop. Dis. 2013; 3(3), 242–251.

74. Singh R., Geetanjali. Asparagus racemosus: a review on its phytochemical and therapeutic potential. Nat. Prod. Res. 2016; 30(17), 1896–908.

75. Rajesh Garg, VB Gupta. A comparative study of milk and aqueous decoction of Asparagus racemosus on serum prolacti level of lactating female rats. Inventi Journals Pvt. Ltd. Dostupné z: http://inventi.in/journal/article/impact/3/62/ethnopharmacology/pi

76. Gupta M., Shaw B. A Double-Blind Randomized Clinical Trial for Evaluation of Galactogogue Activity of Asparagus racemosus Willd. Iran J. Pharm. Res. 2011; 10(1), 167–172.

77. Hamed, Rawia S. Effect of aqueous extracts of Galega officinalis and Asparagus racemosus supplementationon development of mammary gland, milk yield and its impact on the productivity of rabbit does. Egypt Poult. Sci. J. 2016; 36(4), 985–1004.

78. Singh A., Sinha B. Pharmacological significance of shatavari; The Queen of herbs. Int. J. Phytomedicine 2015; 6(4), 477–488.

79. Tyler VM, Premila MS. Ayurvedic Herbs: A Clinical Guide to the Healing Plants of Traditional Indian Medicine. Routledge 2012.